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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
KCNH8
All Species:
22.12
Human Site:
S774
Identified Species:
54.07
UniProt:
Q96L42
Number Species:
9
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q96L42
NP_653234.2
1107
123804
S774
I
R
V
S
R
S
N
S
P
K
T
K
Q
E
I
Chimpanzee
Pan troglodytes
XP_001162672
1107
123869
S774
I
R
V
S
R
S
N
S
P
K
T
K
Q
E
I
Rhesus Macaque
Macaca mulatta
XP_001087569
1107
123826
S774
I
R
V
S
R
S
N
S
P
K
T
K
Q
E
I
Dog
Lupus familis
XP_542769
1108
123784
S775
S
R
V
S
S
S
H
S
P
K
N
K
Q
E
I
Cat
Felis silvestris
Mouse
Mus musculus
P59111
1102
123258
S774
I
R
V
S
S
A
N
S
P
K
T
K
Q
E
A
Rat
Rattus norvegicus
Q9QWS8
1102
123212
S774
I
R
V
S
S
A
N
S
P
K
T
K
Q
E
A
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001508200
1155
129668
P822
I
R
V
C
S
S
N
P
A
R
T
R
H
E
T
Chicken
Gallus gallus
Q9PT84
526
59775
I212
A
I
P
F
D
L
L
I
F
R
S
G
S
D
E
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_001922595
1119
124151
S779
V
V
D
G
T
E
D
S
D
G
T
E
N
S
H
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q02280
1174
126352
A830
V
A
T
T
S
S
A
A
A
G
A
G
V
S
G
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.4
99.1
95.8
N.A.
92.2
92.1
N.A.
83.2
22.4
N.A.
57.2
N.A.
30.4
N.A.
N.A.
N.A.
Protein Similarity:
100
99.6
99.3
97.9
N.A.
95.6
95.3
N.A.
88.1
32.7
N.A.
68.5
N.A.
49.5
N.A.
N.A.
N.A.
P-Site Identity:
100
100
100
73.3
N.A.
80
80
N.A.
46.6
0
N.A.
13.3
N.A.
6.6
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
100
80
N.A.
86.6
86.6
N.A.
60
20
N.A.
33.3
N.A.
26.6
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
10
10
0
0
0
20
10
10
20
0
10
0
0
0
20
% A
% Cys:
0
0
0
10
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
10
0
10
0
10
0
10
0
0
0
0
10
0
% D
% Glu:
0
0
0
0
0
10
0
0
0
0
0
10
0
70
10
% E
% Phe:
0
0
0
10
0
0
0
0
10
0
0
0
0
0
0
% F
% Gly:
0
0
0
10
0
0
0
0
0
20
0
20
0
0
10
% G
% His:
0
0
0
0
0
0
10
0
0
0
0
0
10
0
10
% H
% Ile:
60
10
0
0
0
0
0
10
0
0
0
0
0
0
40
% I
% Lys:
0
0
0
0
0
0
0
0
0
60
0
60
0
0
0
% K
% Leu:
0
0
0
0
0
10
10
0
0
0
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
60
0
0
0
10
0
10
0
0
% N
% Pro:
0
0
10
0
0
0
0
10
60
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
60
0
0
% Q
% Arg:
0
70
0
0
30
0
0
0
0
20
0
10
0
0
0
% R
% Ser:
10
0
0
60
50
60
0
70
0
0
10
0
10
20
0
% S
% Thr:
0
0
10
10
10
0
0
0
0
0
70
0
0
0
10
% T
% Val:
20
10
70
0
0
0
0
0
0
0
0
0
10
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _